Ducati Panigale V4 S First Ride Review - Top Dog

The Chang International Circuit is F-A-S-T. Long straights, hard acceleration zones, and harder braking points – all stitched together with some truly terrifying high-speed corners. Common sense would suggest it’s not exactly the ideal playground for first-timers on a top-dog, litre-class superbike. But when it’s about Ducati, there’s always some room for surprise. Which is why they flew me to this MotoGP track to get my first taste of the 2025 Panigale V4 S.

2025 Ducati Panigale V4 S: What’s New and Why It Matters

Now, this is a big deal. This is about the brand-new Panigale V4 – the flagship from Bologna. As you’d expect, Ducati has been shouting from the rooftops that this is the best-ever, fastest-ever, and most forward-looking Panigale, ever. A manufacturer hyping its latest product? Business as usual, or are they actually telling the truth?

Well, after spending a full day on it, lapping a racetrack under the sweltering Buriram sun, we think we have the answer. The new Panigale V4 is fan-effing-tastic!

Now, of course, a whole lot of fine-tuning and fresh changes have gone into this 7G Panigale. But let’s start with the familiar. The 2025 version is still propelled by the same 1,103cc V4 engine. It’s still blazingly red. And it’s still very desirable. Some might complain the design has softened, but it grows on you with time. Two minutes, to be precise. That’s how long it took me to fall for it.

Ducati Panigale V4 S Engine, Frame and Suspension Updates Explained

Let’s move to the finer details. The frame is all-new, and so is the dual-sided swingarm, which replaces the gorgeous single-sided unit of the outgoing model. Why the change? Because it’s all about form following function here. The new swingarm reduces lateral stiffness by a whopping 37%. It’s a similar story with the front frame – it claims to bring lateral rigidity down by an impressive 40%.

There are also new electronics, an updated Öhlins semi-electronic suspension setup, a beefed-up braking package, and more. Now, I could go on and type out the entire brochure for you, but I’m pretty sure I’d run out of space on these pages. So, let’s cut to the chase and talk about what really matters: the riding experience.

If you’ve ridden the original Panigale V4, especially the first-gen from 2017, you’ll remember what an assassin it was. Relentless. Rigid. Unforgiving. It was hot-blooded and temperamental, like a heavyweight boxer dialled up to 11. A lethal weapon that wouldn’t hesitate to chew you up and spit you out for the slightest mistake.

How the 2025 Panigale V4 S Rides on Track

Ducati realised the problem quickly, which is why the later versions of the Panigale V4 became a bit less feverish and a little more friendly. But, as they say, a leopard doesn’t change its spots – the red mist never fully cleared from the Panigale’s head. Well, that was until now. The new Panigale V4 is a complete rethink. It’s no longer out for your blood the moment you twist the throttle. Instead, this one gently holds your hand, calms your nerves, and then blows your pants off – same, same, but very different.

It is noticeably friendlier to ride – something that was clear from the very first lap. It feels lighter, roomier, and far less physically demanding. At 213bhp, the V4 motor still produces more or less the same power, but these 2025-spec horses are far more accessible.

For instance, the throttle no longer feels like you’re cracking open the lid of a nuclear reactor. The response is sharp but measured, and not barking mad. Make no mistake, the acceleration is still mind-tinglingly brutish, and a slight twist of the wrist will still leave you breathless – just not in a suicidal way.

And those long straights? The Panigale eats them up like Pac-Man. The acceleration is jaw-dropping. But before you can even pick your jaw off the floor, you’re hard on the brakes, and down it goes again on the floor – the stopping power from the new Brembo Hypure brakes are simply sensational.

What’s more, you now get Race eCBS – a linked braking system that automatically engages the rear brake for trail braking when you grab the front lever. The result? Tighter lines into apexes and a sense that, just maybe, you’re the second coming of Marc Márquez.

And last but not least, the handling and electronics. While the old Panigale needed to be muscled into corners at high speeds, this one flows with you, like an extension of your body. You can hurl it into a bend without a second thought, and it’ll rocket out the other side, gripping the tarmac like a leech. Honestly, it feels more like a middleweight than a full-fat litre-class machine.

Adding to that sense of confidence is its suite of stellar electronics, including the new DVO (Ducati Vehicle Observer), which constantly tweaks wheelie control and traction control in real time. Not only does it keep you from launching yourself into space but also helps you post faster lap times.

2025 Ducati Panigale V4 S Verdict: Should You Buy One?

As far as I’m concerned, the Panigale V4 S is faultless. It’s blisteringly fast and drop-dead gorgeous, and now it’s also friendlier and more welcoming than ever. Regardless of your skill level, it’s a motorcycle that urges you to push harder, without punishing your body or bruising your ego. The only downside? That price tag. At ₹36.5 lakh (ex-showroom), it demands a heck of a lot of money. But, then, in return, you also get a heck of a lot of bike.